GENETIC ANALYSIS OF BLOOD MOLECULAR PHENOTYPES REVEALS COMMON PROPERTIES IN THE REGULATORY NETWORKS AFFECTING COMPLEX TRAITS

Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

Abstract We evaluate the shared genetic regulation of mRNA molecules, proteins and metabolites derived from whole blood from 3029 human donors.We find abundant allelic heterogeneity, where multiple variants regulate a particular molecular phenotype, and pleiotropy, where a single variant associates with multiple molecular phenotypes over multiple g

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The effects of water control on the survival and growth of Alternanthera philoxeroides in the vegetative reproduction and seedling stages

Abstract Number Holders Alternanthera philoxeroides (Martius) is an infamous invasive alien plant that is widely distributed in aquatic and terrestrial habitats.To investigate the vegetative reproduction, growth, survival strategy, and the function of leaves in fragment of A.philoxeroides under different water conditions, two water control experime

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Transcriptomic and Phytohormone Metabolomics Provide Insight into the Changes in Citrus limon Infected by Citrus yellow vein clearing virus

Background: Citrus yellow vein-clearing virus (CYVCV) is a Mandarivirus that causes great economic losses in lemon production.CYVCV infection is associated with obvious yellow vein-clearing disease symptoms and is directly regulated by plant hormone responses.Methods: To understand how lemon plants respond to CYVCV infection, we performed transcrip

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Stigma gets in my way: Factors affecting client-provider communication regarding childbearing among people living with HIV in Uganda.

Many HIV-affected couples living in sub-Saharan Africa desire to have children, but few quantitative studies have examined support for their childbearing needs.Our Rotary Switches study explored client-provider communication about childbearing and safer conception among HIV clients in Uganda.400 Ugandan HIV clients in committed relationships and wi

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Gradient-wise search strategy for blind image deblurring

Blind image deblurring is a long-standing challenging problem to improve the sharpness of an image as a prerequisite step.Many iterative methods are widely used for the deblurring image, but care must be taken to ensure that the methods have fast convergence and accuracy solutions.To address these problems, we propose a gradient-wise step size sear

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